Search results for " High-Intensity Focused Ultrasound ablation"

showing 9 items of 9 documents

Intraoperative imaging findings in transcranial MR imaging-guided focused ultrasound treatment at 1.5T may accurately detect typical lesional finding…

2020

To assess the intraoperative neuroimaging findings in patients treated with transcranial MR-guided focused ultrasound (tcMRgFUS) thalamotomy using 1.5T equipment in comparison with the 48-h follow-up.Fifty prospectively enrolled patients undergoing unilateral tcMRgFUS thalamotomy for either medication-refractory essential tremor (n = 39) or Parkinson tremor (n = 11) were included. Two radiologists evaluated the presence and size of concentric lesional zones (zone I, zone II, and zone III) on 2D T2-weighted sequences acquired intraoperatively after the last high-energy sonication and at 48 h. Sonication parameters including number of sonications, delivered energy, and treatment temperatures …

AdultMalemedicine.medical_specialtyessential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson disease; stereotaxic techniqueshigh-intensity focused ultrasound ablationInterventional magnetic resonance imagingmedicine.medical_treatmentStereotaxic techniqueSonicationThalamusmedicineHumansRadiology Nuclear Medicine and imagingessential tremorNeuroradiologyAgedUltrasonographyAged 80 and overIntraoperative Caremedicine.diagnostic_testEssential tremorThalamotomybusiness.industryUltrasoundinterventional magnetic resonance imagingSettore MED/37 - NeuroradiologiaInterventional radiologyGeneral Medicinestereotaxic techniquesMiddle Agedmedicine.diseaseMagnetic Resonance ImagingParkinson diseaseCoagulative necrosisSurgery Computer-AssistedStereotaxic techniqueSettore MED/26 - NeurologiaFemaleRadiologySettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness
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Transcranial magnetic resonance imaging-guided focused ultrasound treatment at 1.5 T: a retrospective study on treatment and patient-related paramete…

2020

Objective: To present a retrospective analysis of patient- and sonication-related parameters of a group of patients treated with a transcranial magnetic resonance imaging (MRI)-guided focused ultrasound (tcMRgFUS) system integrated with a 1.5-T MRI unit. Methods: The data obtained from 59 patients, who underwent the tcMRgFUS procedure from January 2015 to April 2019, were retrospectively reviewed for this study. The following data, among others, were mainly collected: skull density ratio (SDR), skull area (SA), number of available transducer elements (Tx), and estimated focal power at target (FP). For each of the four different treatment stages, we calculated the number of sonication proces…

Interventional magnetic resonance imagingMaterials Science (miscellaneous)medicine.medical_treatmentParkinson's diseaseEssential TremorBiophysicsGeneral Physics and Astronomy01 natural sciencesFocused ultrasound0103 physical sciencesmedicinePlane orientationInterventional Magnetic Resonance ImagingPhysical and Theoretical Chemistry010306 general physicsMathematical Physicsmedicine.diagnostic_testbusiness.industryThalamotomySettore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaMagnetic resonance imagingRetrospective cohort studystereotaxic techniqueslcsh:QC1-999Settore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Parkinson Disease.essential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson's disease; stereotaxic techniquesCoronal planeStereotaxic techniqueHigh-Intensity Focused Ultrasound AblationStereotaxic TechniqueSettore MED/26 - NeurologiaNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapialcsh:Physics
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Preliminary experience with a transcranial magnetic resonance-guided focused ultrasound surgery system integrated with a 1.5-T MRI unit in a series o…

2018

OBJECTIVETranscranial magnetic resonance–guided focused ultrasound surgery (tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of neurological disorders such as essential tremor (ET), idiopathic asymmetrical tremor-dominant Parkinson’s disease (PD), and neuropathic pain. In this clinical series the authors present the preliminary results achieved with the world’s first tcMRgFUS system integrated with a 1.5-T MRI unit.METHODSThe authors describe the results of tcMRgFUS in a sample of patients with ET and with PD who underwent the procedure during the period from January 2015 to September 2017. A monolateral ventralis intermedius nucleus (VIM) thalamic ablation was pe…

MaleParkinson's diseaseMovement disordershigh-intensity focused ultrasound ablationIntraoperative Neurophysiological Monitoringmedicine.medical_treatmentinterventional030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery0302 clinical medicineThalamusEssential tremorSettore MED/27 - NeurochirurgiaUltrasoundSettore MED/37 - NeuroradiologiaParkinson DiseaseGeneral MedicineMiddle AgedAblationMagnetic Resonance ImagingTreatment OutcomeNeuropathic painBBB = blood-brain barrier; ET = essential tremor; FRFSE = fast recalled FSE; FSE = fast spin echo; FSPGR = fast spoiled gradient echo; FTM = Fahn-Tolosa-Marin; HI-FU = high-intensity focused ultrasound; MRI; MRgFUS; MS = multiple sclerosis; PD = Parkinson’s disease; Parkinson’s disease; QUEST = Quality of Life in Essential Tremor; SWAN = susceptibility-weighted angiography; UPDRS = Unified Parkinson’s Disease Rating Scale; VIM = ventralis intermedius nucleus; brain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance–guided focused ultrasound surgery; stereotactic technique; tcMRgFUS = transcranial magnetic resonance–guided focused ultrasound surgerySettore MED/26 - NeurologiaFemaleRadiologymedicine.symptombrain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance-guided focused ultrasound surgery; mrgfus; mri; parkinson's disease; stereotactic techniqueMRIAdultmedicine.medical_specialtybrainEssential Tremormagnetic resonance–guided focused ultrasound surgery03 medical and health sciencesmedicineHumansmagnetic resonance-guided focused ultrasound surgeryUltrasonography InterventionalAgedThalamotomybusiness.industryMRgFUSmedicine.diseasestereotactic techniqueparkinson's diseaseParkinson’s diseaseSurgeryNeurology (clinical)businessSettore MED/36 - Diagnostica Per Immagini E Radioterapia030217 neurology & neurosurgeryFollow-Up StudiesNeurosurgical focus
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Transcranial magnetic resonance-guided focused ultrasound surgery at 1.5T: a technical note.

2019

Magnetic resonance-guided focused ultrasound is one of the emerging non-invasive technologies offering both image guidance and thermal monitoring. In recent years transcranial application of this technology is starting to impact heavily the neuroscience field. We present here the imaging protocol and the technological methods successfully used with a transcranial magnetic resonance-guided focused ultrasound system certified for clinical treatments of functional neurological disorders, integrated for the first time with a 1.5T magnetic resonance scanner. Compared to the body radiofrequency coil (the one commonly used with transcranial magnetic resonance-guided focused ultrasound system integ…

Maleminimally invasive surgical procedureComputer sciencebraininterventionalSignal-To-Noise RatioNeurosurgical ProcedureMagnetic Resonance Imaging InterventionalFocused ultrasoundNeurosurgical Procedures030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery03 medical and health sciences0302 clinical medicinemedicinemagnetic resonance imagingHumansGeneral NeuroradiologyRadiology Nuclear Medicine and imagingImage guidanceAgedmedicine.diagnostic_testtomography X-ray computedMagnetic resonance scannerinterventional magnetic resonance imagingSettore MED/37 - NeuroradiologiaMagnetic resonance imagingTechnical noteGeneral MedicineSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)minimally invasive surgical proceduresstereotactic techniqueTreatment Outcomebrain; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; minimally invasive surgical procedures; stereotactic techniques; aged; female; high-intensity focused ultrasound ablation; humans; male; neurosurgical procedures; signal-to-noise ratio; tomography X-ray computed; treatment outcome; magnetic resonance imaging; interventionalElectromagnetic coilstereotactic techniquesHigh-Intensity Focused Ultrasound AblationFemaleNeurology (clinical)Settore MED/36 - Diagnostica Per Immagini E RadioterapiaTomography X-Ray Computed030217 neurology & neurosurgeryHumanRadiofrequency coilBiomedical engineeringThe neuroradiology journal
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Chirurgia trans-cranica mediante ultrasuoni focalizzati ad alta intensità su guida RM: esperienza preliminare a 1,5T

2015

Da qualche anno la chirurgia mediante ultrasuoni focalizzati ad alta intensità guidati da Risonanza Magnetica (Magnetic Resonance guided Focused Ultrasound Surgery, MRgFUS) si sta diffondendo anche in Italia per la palliazione del dolore da metastasi ossee, per il trattamento di tumori ossei primitivi (benigni e non), dei fibromi e dell’adenomiosi uterina; sono già stati inoltre pubblicati i risultati preliminari del trattamento di alcuni tumori epatici, pancreatici, prostatici e della mammella mediante MRgFUS. Questa innovativa tecnica prevede l’utilizzo di un’apparecchiatura di Risonanza Magnetica per il monitoraggio della procedura e sfrutta le caratteristiche fisico- meccaniche degli …

Settore MED/27 - NeurochirurgiaBrain High-Intensity Focused Ultrasound ablation Interventional Magnetic Resonance Imaging Minimally Invasive Surgical Procedures Stereotactic TechniquesSettore MED/37 - Neuroradiologia
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Combining split-and-merge and multi-seed region growing algorithms for uterine fibroid segmentation in MRgFUS treatments

2016

Uterine fibroids are benign tumors that can affect female patients during reproductive years. Magnetic resonance-guided focused ultrasound (MRgFUS) represents a noninvasive approach that uses thermal ablation principles to treat symptomatic fibroids. During traditional treatment planning, uterus, fibroids, and surrounding organs at risk must be manually marked on MR images by an operator. After treatment, an operator must segment, again manually, treated areas to evaluate the non-perfused volume (NPV) inside the fibroids. Both pre- and post-treatment procedures are time-consuming and operator-dependent. This paper presents a novel method, based on an advanced direct region detection model, …

SpeedupUterine fibroidsImage ProcessingBiomedical EngineeringThermal ablation02 engineering and technologyMagnetic Resonance Imaging InterventionalFocused ultrasound030218 nuclear medicine & medical imaging03 medical and health sciencesComputer-Assisted0302 clinical medicineImage Processing Computer-Assisted0202 electrical engineering electronic engineering information engineeringmedicineHumansSegmentationRadiation treatment planningSplit-and-merge segmentationSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniMRgFUS treatmentsInterventionalLeiomyomaMulti-seed adaptive region growingbusiness.industrymedicine.diseaseMagnetic Resonance Imagingfemale genital diseases and pregnancy complicationsComputer Science ApplicationsAutomatic segmentation MRgFUS treatments Multi-seed adaptive region growing Split-and-merge segmentation Uterine fibroids Algorithms Female High-Intensity Focused Ultrasound Ablation Humans Leiomyoma Magnetic Resonance Imaging Magnetic Resonance Imaging Interventional Image Processing Computer-AssistedMRgFUS treatmentRegion growingAutomatic segmentation; MRgFUS treatments; Multi-seed adaptive region growing; Split-and-merge segmentation; Uterine fibroids; Algorithms; Female; High-Intensity Focused Ultrasound Ablation; Humans; Leiomyoma; Magnetic Resonance Imaging; Magnetic Resonance Imaging Interventional; Image Processing Computer-AssistedHigh-Intensity Focused Ultrasound AblationFemale020201 artificial intelligence & image processingAutomatic segmentationbusinessMerge (version control)AlgorithmAlgorithmsUterine fibroidsMedical & Biological Engineering & Computing
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MRgFUS results Italy

2017

PURPOSE: To present our preliminary results achieved with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. Moreover, to our knowledge, this is the world-first tcMRgFUS system ever installed on a 1.5T MRI unit. Technical issues faced to achieve a safe and effective treatment will be discussed focusing on MR high-resolution live imaging and thermometry sequences optimization. METHOD AND MATERIALS: Patient enrollment was based on indication for functional neurosurgery and evidence of medication-refractory disease; a detailed medical history has been collected together with a complete clinical examin…

Stereotaxic TechniquesBrain; High-Intensity Focused Ultrasound ablation; Magnetic Resonance Imaging Interventional; Minimally Invasive Surgical Procedures; Stereotaxic TechniquesHigh-Intensity Focused Ultrasound ablationSettore MED/27 - NeurochirurgiaBrainSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaMinimally Invasive Surgical ProcedureMagnetic Resonance Imaging InterventionalSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Restoring Neurological Physiology: The Innovative Role of High-Energy MR-Guided Focused Ultrasound (HIMRgFUS). Preliminary Data from a New Method of …

2017

Background Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for intentional tremor, and of the subthalamic nucleus for parkinsonian resting tremor, have been introduced in clinical practice for patients refractory to medical treatment. The combination of high-energy focused ultra-sound (HIFUS) with sophisticated magnetic resonance (MR) instrumentation, together with accurate knowledge of the stereotactic brain coordinates, represents a revolution in neuromodulation. Methods At the Neurosurgical Clinic and the Radiology Department of the University of Palermo,, tw…

medicine.medical_specialtyParkinson's diseaseDeep brain stimulationmedicine.medical_treatmentNeurosurgical ProcedureSeverity of Illness IndexNeurosurgical ProceduresFocused ultrasoundMRI-guided focused ultrasound (MRgFUS)03 medical and health sciences0302 clinical medicineTremormedicineHumans030212 general & internal medicineResting tremorVentral Thalamic Nucleimedicine.diagnostic_testEssential tremorSettore MED/27 - Neurochirurgiabusiness.industryEssential tremor; functional neurosurgery; lesioning surgery; MRI-guided focused ultrasound (MRgFUS); Parkinson’s disease; brain; high-intensity focused ultrasound ablation; humans; magnetic resonance imaging; neurosurgical procedures; severity of illness index; surgery computer-assisted; tremor; ventral thalamic nucleiSettore MED/37 - NeuroradiologiaBrainMagnetic resonance imagingLesioning surgerymedicine.diseaseMagnetic Resonance ImagingNeuromodulation (medicine)nervous system diseasesSurgerySubthalamic nucleusFunctional neurosurgerySurgery Computer-AssistedParkinson’s diseaseEssential tremorHigh-Intensity Focused Ultrasound AblationSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness030217 neurology & neurosurgeryHuman
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Transcranial Magnetic Resonance-Guided Focused Ultrasound Surgery for Brain Tumor Ablation: Are We Ready for This Challenging Treatment?

2018

The treatment of high-grade gliomas (HGGs) remains a challenge for modern therapy. The prognosis for these patients has been poor. The median patient survival after diagnosis has been ∼1 year with surgery and/or radiotherapy and temozolomide.1 The need for a histological diagnosis of tumor tissue in each case and the importance of decompression in symptomatic patients are well established, and extensive surgical resection has been shown to significantly prolong survival. Several factors play a role in the prognosis of patients with HGG, including age, performance status using the Karnofsky performance scale, and the extent of resection.2, 3 At present, the standard therapy for HHG consists …

medicine.medical_specialtymedicine.medical_treatmentBrain tumor01 natural sciencesMagnetic resonance guided focused ultrasound surgeryBrain Neoplasm03 medical and health sciences0302 clinical medicine0103 physical sciencesmedicineHumans010306 general physicsSettore MED/27 - Neurochirurgiabusiness.industryBrain NeoplasmsSettore MED/37 - NeuroradiologiaBrainAblationmedicine.diseaseMagnetic Resonance Imagingbrain; brain neoplasms; high-intensity focused ultrasound ablation; humans; magnetic resonance imagingHigh-Intensity Focused Ultrasound AblationSurgeryNeurology (clinical)RadiologySettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness030217 neurology & neurosurgeryHumanWorld neurosurgery
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